Ebola, Marburg and Zika Viruses

Ebola virus disease (EVD), also known as Ebola haemorrhagic fever, is a rare but serious and often fatal infection that affects people. The virus is disseminated in the human population by human-to-human transmission once it is transmitted to people from wild animals. Ebola is an uncommon but fatal virus that causes fever, body pains, diarrhoea, and, in some cases, internal and external bleeding. The typical case fatality rate for EVD is roughly 50%. In previous outbreaks, case mortality rates have ranged from 25% to 90%.

Marburg virus disease is a highly contagious disease that produces haemorrhagic fever and has an 88 percent death rate. It belongs to the same family as the Ebola virus, which causes the sickness. Human infection with the Marburg virus is caused by continuous exposure to mines or caves where Rousettus bat populations live. Marburg can spread from person to person via direct contact once an individual has been infected with the virus.

Dengue fever, yellow fever, and West Nile virus are all similar to Zika virus. Zika is mostly transmitted by bites by infected Aedes aegypti mosquitos, although it can also be transferred intra uterinally. Zika can enter into the placenta and damage the foetus if a woman is bitten by an infected mosquito and becomes infected.

• Pathogenesis
• Animal Models
• Therapeutic Approaches